Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK6 ▸ MAPK7 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ CCL2 ▸ NOS1 ▸
CD14 ▸ ICAM1 ▸ IL4 ▸ JUN ▸ CPOX ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPH1 ▸ PTBP2 ▸
HNRNPF ▸ IL33 ▸ IL3 ▸ IL15 ▸ IL32 ▸ IL37 ▸ IL21 ▸
IL19 ▸ IL16 ▸ IL22 ▸ IL24 ▸ IL11 ▸ IL31 ▸ IL9 ▸
IL7 ▸ IL20 ▸ IL34 ▸ IL26 ▸ IL25 ▸ IL27 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP3 ▸ CASP1 ▸ CXCL10 ▸ CASP9 ▸ CASP6 ▸ CASP8 ▸ CASP4 ▸
CASP5 ▸ CASP12 ▸ CASP16 ▸ CASP14 ▸ CASP10 ▸ CASP2 ▸ CASP7 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ CCL3 ▸ TLR1 ▸
ANXA6 ▸ CFP ▸ VEGFA ▸ TLR7 ▸ LANCL1 ▸ TLR5 ▸ TLR8 ▸
CRK ▸ TLR6 ▸ STAT1 ▸ MMP2 ▸ GPI ▸ CD86 ▸ TLR10 ▸
CD79A ▸ CD40 ▸ MMP1 ▸ HMGB1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ CD80 ▸ POLDIP2 ▸ STAT3 ▸ IRF3 ▸ MIP ▸
NOX4 ▸ MMP3 ▸ MYD88 ▸ TP63 ▸ MMP13 ▸ MUC2 ▸ NOX3 ▸
MUC1 ▸ NOX5 ▸ MMP8 ▸ CA2 ▸ MMP14 ▸ TGFB1 ▸ MUC7 ▸
MMP11 ▸ IRAK1 ▸ CXCL1 ▸ MMP12 ▸ MMP15 ▸ RABEPK ▸ MMP7 ▸
MUC16 ▸ MMP24 ▸ MMP27 ▸ MMP17 ▸ MMP16 ▸ CXCL2 ▸ MMP20 ▸
CD46 ▸ MMP21 ▸ MMP10 ▸ MMP28 ▸ MUC4 ▸ MMP26 ▸ MMP25 ▸
MMP19 ▸ TCF4 ▸ TCF21 ▸ IKBKG ▸ TCF23 ▸ TCF19 ▸ MUC6 ▸
MUC13 ▸ MUC17 ▸ TCF25 ▸ MUC22 ▸ TCF12 ▸ TCF20 ▸ MUC19 ▸
TCF24 ▸ MUC20 ▸ MUC8 ▸ TCF3 ▸ MUC12 ▸ MUC21 ▸ MUC15 ▸
TCF7 ▸ TCF15 ▸ CXCL9 ▸ CXCL11 ▸ LEO1 ▸ CDC73 ▸ CTR9 ▸
LYZ ▸ CXCL12 ▸ HLA-DRA ▸ PAF1 ▸ WDR61 ▸ SERPINE1 ▸ HLA-DRB1 ▸
PTGS1 ▸ CXCL13 ▸ LEP ▸ IRF1 ▸ PLA2G4A ▸ CXCL5 ▸ ITGB2 ▸
IRAK4 ▸ CXCL16 ▸ SOD2 ▸ MIPEP ▸ CXCL6 ▸ SOD1 ▸ SOD3 ▸
C1orf228 ▸ CSF3 ▸ CXCL17 ▸ IDO1 ▸ PGF ▸ CXCL3 ▸ CXCL14 ▸
IL23A ▸ PI3 ▸ REL ▸ HDC ▸ PIK3R1 ▸ CRH ▸ PIK3CA ▸
PDCD11 ▸ HGF ▸ SOCS3 ▸ CD83 ▸ SAA1 ▸ MYLIP ▸ IRAK3 ▸
LTB ▸ CSF1 ▸ PLA2G1B ▸ SLC25A10 ▸ EGR1 ▸ ICAM3 ▸ NM ▸
ICAM4 ▸ ICAM2 ▸ NANOS2 ▸ ICAM5 ▸ INS ▸ MUC5AC ▸ IRAK2 ▸
NUP43 ▸ FAS ▸ ARG1 ▸ TBCE ▸ PTGES ▸ IGF1 ▸ CEBPB ▸
SOAT1 ▸ MIF ▸ SLPI ▸ TNPO1 ▸ CCR2 ▸ BPI ▸ SETD2 ▸
EDN1 ▸ CD4 ▸ TNFSF11 ▸ NCF1 ▸ CEBPA ▸ DEFB4B ▸ CREB5 ▸
CREB1 ▸ CREB3 ▸ CAT ▸ IRF7 ▸ CCL4 ▸ FASLG ▸ HDAC1 ▸
DUSP1 ▸ PTX3 ▸ MDM4 ▸ ARF5 ▸ ARF4 ▸ SELP ▸ MAP3K8 ▸
IFI44 ▸ CD69 ▸ HDAC2 ▸ S100A12 ▸ CCL20 ▸ ARF3 ▸ ARF1 ▸
MDM1 ▸ ARF6 ▸ MDM2 ▸ CRP ▸ SRC ▸ IRF2 ▸ HIF1A ▸
IRF8 ▸ IRF4 ▸ ABCC1 ▸ PLD2 ▸ CISH ▸ ARG2 ▸ GP2 ▸
PLD3 ▸ NFKBIB ▸ PLD5 ▸ GP5 ▸ PPARG ▸ GP6 ▸ GP9 ▸
TNFRSF11B ▸ PLD1 ▸ PLD4 ▸ RBBP4 ▸ APOE ▸ PLD6 ▸ CCR7 ▸
RHOA ▸ SLC17A5 ▸ MTOR ▸ PLG ▸ RAC1 ▸ NGF ▸ SERPINB2 ▸
CCL5 ▸ PGD ▸ AGTR2 ▸ CDCA5 ▸ NOD2 ▸ APOB ▸ AVP ▸
BAX ▸ CCR5 ▸ ALB ▸ TRAF6 ▸ PRKCA ▸ CD40LG ▸ ZFP36 ▸
CORT ▸ CCND1 ▸ MAPKAPK2 ▸ BCL2 ▸ TREM1 ▸ IL17D ▸ JAK2 ▸
APC ▸ GJA1 ▸ BDNF ▸ AHR ▸ SP1 ▸ TIMP1 ▸ GIT2 ▸
HBD ▸ ADAM11 ▸ PPARA ▸ CXCR4 ▸ LY96 ▸ HSPG2 ▸ IRF9 ▸
F3 ▸ IFNA4 ▸ RBBP7 ▸ PLAU ▸ IRF5 ▸ LTF ▸ LYN ▸
LPL ▸ PDE4B ▸ BCL10 ▸ STS ▸ SELL ▸ GNRH1 ▸ IL1R1 ▸
CALM3 ▸ IL2RA ▸ CAV1 ▸ ATP5O ▸ TBK1 ▸ LITAF ▸ LIF ▸
EGFR ▸ ODC1 ▸ FCER2 ▸ LCN2 ▸ ATF2 ▸ EIF2AK2 ▸ UCN ▸
TNFSF10 ▸ SAP130 ▸ RAF1 ▸ BTK ▸ AGTR1 ▸ CCR3 ▸ HSPD1 ▸
IL17A ▸ GAL ▸ SUDS3 ▸ BCL3 ▸ SAP30 ▸ SLC27A5 ▸ NA ▸
TNFSF13B ▸ PRL ▸ TFPI ▸ MT3 ▸ MNAT1 ▸ CD2 ▸ NCF2 ▸
IFNA2 ▸ PTK6 ▸ SOCS1 ▸ PRDX2 ▸ CYP3A ▸ PTK7 ▸ SIN3A ▸
PARP1 ▸ MLYCD ▸ MOCOS ▸ P2RX7 ▸ PTK2 ▸ CSRP1 ▸ CCR6 ▸
ATP8A2 ▸ SPP1 ▸ GDNF ▸ ARID4B ▸ ADM ▸ TP53 ▸ RETN ▸
ACP2 ▸ ECM1 ▸ CD44 ▸ IFNA21 ▸ CRAT ▸ ADAM17 ▸ LDLR ▸
CXCR1 ▸ NOTCH1 ▸ IFNA13 ▸ STAT5A ▸ CCR10 ▸ CCR4 ▸ CSE ▸
MAP2K1 ▸ CD276 ▸ LIPA ▸ IFNA14 ▸ RELB ▸ ECM2 ▸ IFNA17 ▸
SLC22A3 ▸ ETS2 ▸ TGFB2 ▸ CCR1 ▸ CEL ▸ GCHFR ▸ IFNA16 ▸
CEBPD ▸ IFNA10 ▸ JAK1 ▸ PRG4 ▸ NEDD9 ▸ FGB ▸ APP ▸
IL2RB ▸ IKBKAP ▸ CD8A ▸ IFNA6 ▸ CCR9 ▸ SPHK1 ▸ PRG2 ▸
MOK ▸ MSH3 ▸ IFNA1 ▸ PHKA2 ▸ MAP3K14 ▸ IFNA8 ▸ SETBP1 ▸
CCR8 ▸ PRG3 ▸ IFNA5 ▸ ACE ▸ NLRP3 ▸ IFNA7 ▸ TGFB3 ▸
CCL24 ▸ UCP2 ▸ HDAC3 ▸ MSH5 ▸ F2R ▸ OLR1 ▸ NOD1 ▸
OCLN ▸ CADM1 ▸ CAMP ▸ SYK ▸ NOTCH4 ▸ CXCR2 ▸ RAC2 ▸
APCS ▸ CAV3 ▸ TRAM1 ▸ PLAUR ▸ NOTCH3 ▸ LTA ▸ F2RL1 ▸
PAM ▸ TNFRSF1B ▸ SAA2 ▸ WAS ▸ MSH4 ▸ ANXA1 ▸ C9orf3 ▸
SERPING1 ▸ MAF ▸ PTPN11 ▸ TRAM2 ▸ NOTCH2 ▸ THBD ▸ IGFBP3 ▸
TF ▸ TYK2 ▸ CNR2 ▸ SLCO6A1 ▸ GIF ▸ BCL5 ▸ ABCB1 ▸
BCL9 ▸ BCL6 ▸ SH3D19 ▸ MSH6 ▸ TNP2 ▸ FBXO32 ▸ HDAC11 ▸
SAA4 ▸ ALG1 ▸ TXN ▸ CD55 ▸ ATF3 ▸ PCBD1 ▸ TNFRSF1A ▸
CRYGEP ▸ NEU1 ▸ EIF4EBP1 ▸ SIGLEC7 ▸ S100A8 ▸ TNP1 ▸ ABCA1 ▸
PLIN2 ▸ MSH2 ▸ GHR ▸ EDN3 ▸ EDN2 ▸ NPY4R ▸ CNP ▸
STX1A ▸ TECR ▸ NEU4 ▸ GPX8 ▸ S12 ▸ LPO ▸ CAV2 ▸
GSK3B ▸ UPK3B ▸ GIT1 ▸ CEBPZ ▸ PGP ▸ GFAP ▸ S7 ▸
HDAC6 ▸ ITGAX ▸ FXR2 ▸ COA3 ▸ CYBB ▸ NEU2 ▸ FADD ▸
CETP ▸ SIGIRR ▸ CCND2 ▸ UBL3 ▸ CIITA ▸ SMC3 ▸ ADCY9 ▸
ANXA5 ▸ NAALADL1 ▸ TYR ▸ POMC ▸ GPX7 ▸ GPX6 ▸ GATA2 ▸
GATA3 ▸ PPARGC1A ▸ PRKAB2 ▸ ISG15 ▸ LOX ▸ SLC7A2 ▸ PRKAG2 ▸
CD19 ▸ PRKAB1 ▸ JUND ▸ PLCG1 ▸ CHD4 ▸ SMC6 ▸ PLTP ▸
JAK3 ▸ POU2F2 ▸ NEU3 ▸ PRDX1 ▸ SCARB1 ▸ ICOSLG ▸ TSPO ▸
EPB42 ▸ SLC2A1 ▸ CES1 ▸ HP ▸ GPX3 ▸ CDC42 ▸ HMGCR ▸
VIP ▸ CX3CL1 ▸ FGFR3 ▸ GPX2 ▸ MT4 ▸ A2M ▸ CTRL ▸
NPPA ▸ MRXS5 ▸ CD1A ▸ CD8B ▸ CD28 ▸ MTA2 ▸ PLAT ▸
SMC2 ▸ WNT2 ▸ MAP3K7 ▸ ALPI ▸ SMC4 ▸ CTLA4 ▸ CD38 ▸
JUNB ▸ PGC ▸ PRKAA1 ▸ GAST ▸ PRKAA2 ▸ AQP5 ▸ CCL18 ▸
CYP2B6 ▸ DDX58 ▸ GPX5 ▸ SMC5 ▸ BIRC3 ▸ COA6 ▸ ELAVL1 ▸
GPX1 ▸ S11 ▸ COA4 ▸ ACHE ▸ IFIT2 ▸ GPX4 ▸ MET ▸
TRAF1 ▸ TOLLIP ▸ FPR1 ▸ PTX4 ▸ RPTOR ▸ PRKAG1 ▸ FXR1 ▸
TFRC ▸ SEC14L2 ▸ ARC ▸ CTSB ▸ CDH13 ▸ AGXT ▸ VIPR1 ▸
OXTR ▸ DDIT3 ▸ MARCKS ▸ COA1 ▸ COA5 ▸ ACO1 ▸ EIF4E ▸
PRDX5 ▸ INSR ▸ SMAD4 ▸ FOSL1 ▸ SDC4 ▸ CCL1 ▸ KITLG ▸
CROT ▸ SLC11A2 ▸ ERP29 ▸ CAPN12 ▸ VWF ▸ CAPN3 ▸ GALT ▸
MCM2 ▸ ADCY4 ▸ MUC5B ▸ G6PD ▸ PRKACB ▸ RIPK2 ▸ CYP4F8 ▸
MAP2K6 ▸ RHO ▸ S100A9 ▸ HPGDS ▸ CX3CR1 ▸ RHOB ▸ PARP12 ▸
TPX2 ▸ SERPINB6 ▸ TBL1X ▸ LAMP2 ▸ PARP2 ▸ PRKACG ▸ ETS1 ▸
AMBP ▸ MCM6 ▸ SDC2 ▸ TPO ▸ VDR ▸ CES3 ▸ TFAP2A ▸
PPP2CA ▸ MCM4 ▸ TNFSF13 ▸ MAP2K2 ▸ PLA2G7 ▸ PARP6 ▸ PARP4 ▸
PARP16 ▸ C5AR1 ▸ PTHLH ▸ STAR ▸ MCM5 ▸ IRG1 ▸ PARP10 ▸
MST1R ▸ HSP90AA1 ▸ NCF4 ▸ IKBKE ▸ ADCY8 ▸ TRIM63 ▸ SST ▸
GATA5 ▸ CTSL ▸ CAPN14 ▸ CCL4L2 ▸ IL1RAP ▸ PKD3 ▸ MEPE ▸
USP7 ▸ ASS1 ▸ FEV ▸ CYP4F3 ▸ SIRT1 ▸ MT-CYB ▸ C1QA ▸
PDGFA ▸ ADCY6 ▸ CAPN7 ▸ GATA1 ▸ CORO2A ▸ IL6R ▸ IL2RG ▸
ABL1 ▸ NPR1 ▸ MCS ▸ MTA1 ▸ SPHK2 ▸ CES2 ▸ KCNMA1 ▸
CNR1 ▸ CLDN1 ▸ ELANE ▸ GSR ▸ NFKBIZ ▸ PARP11 ▸ ADCY3 ▸
TBL1XR1 ▸ PRKAR1A ▸ APOA1 ▸ LAMP1 ▸ PPP2R2B ▸ SP100 ▸ KLK3 ▸
LAMP3 ▸ CAPN6 ▸ NANOS1 ▸ IL18BP ▸ REG3A ▸ HDAC10 ▸ CADM2 ▸
FGF9 ▸ PRDM1 ▸ ACAN ▸ SMAD7 ▸ PLN ▸ TPGS2 ▸ PARP3 ▸
PECAM1 ▸ IFN1@ ▸ SLC5A1 ▸ CAPN9 ▸ PDCD1LG2 ▸ RPS6KB1 ▸ MICE ▸
IGH ▸ GLA ▸ FPR2 ▸ MCM3 ▸ ADCY2 ▸ CTNNB1 ▸ FGF21 ▸
PPP2R1A ▸ NDUFAB1 ▸ PRKAR1B ▸ KHSRP ▸ GATA4 ▸ CD58 ▸ IL13RA1 ▸
MARCO ▸ CD1D ▸ FGF2 ▸ SREBF1 ▸ TAT ▸ SMN1 ▸ EDNRA ▸
RSAD2 ▸ TPGS1 ▸ ADCY7 ▸ SPAG8 ▸ CAPN1 ▸ HDAC4 ▸ EPB41 ▸
IDS ▸ CAPN5 ▸ AQP1 ▸ TIMP3 ▸ OSM ▸ HDAC7 ▸ CYP4F11 ▸
MBD3 ▸ NQO1 ▸ PDCD2 ▸ TXNRD2 ▸ NR4A1 ▸ ADCY10 ▸ SLC9A1 ▸
CYP4F22 ▸ CAPN2 ▸ BDKRB1 ▸ PDGFB ▸ CPZ ▸ EPS15 ▸ MLST8 ▸
FCGR1A ▸ FMR1 ▸ CADM3 ▸ NPY ▸ CD5 ▸ C1QB ▸ CLU ▸
ESAM ▸ MAP2K3 ▸ NCOR1 ▸ AQP2 ▸ LAMP5 ▸ P2RX4 ▸ PLEK ▸
ADCY5 ▸ LTC4S ▸ PKD2 ▸ RNPEP ▸ HCLS1 ▸ ADCY1 ▸ PLCG2 ▸
QRICH2 ▸ EPS8 ▸ PIR ▸ NR1I2 ▸ AQP4 ▸ AGT ▸ PTEN ▸
CYP4F2 ▸ TUBGCP2 ▸ DST ▸ PARP14 ▸ ITGB1 ▸ FST ▸ PKD1 ▸
KLF4 ▸ ITGAL ▸ CADM4 ▸ S1PR1 ▸ ERP44 ▸ GATA6 ▸ PMPCB ▸
HDAC9 ▸ PGR ▸ PARP9 ▸ CAPN15 ▸ RASIP1 ▸ DOK3 ▸ HDAC5 ▸
KCNH4 ▸ CD9 ▸ ISG20 ▸ PRKCB ▸ PARP15 ▸ PRX ▸ MAL ▸
QRICH1 ▸ HAMP ▸ LRP1 ▸ FOXP3 ▸ NTRK1 ▸ AKT1S1 ▸ USP14 ▸
ERF ▸ PRTN3 ▸ CYP1A2 ▸ C4BPA ▸ BCR ▸ NTF3 ▸ HDAC8 ▸
CYP4F12 ▸ S1PR3 ▸ CAPN8 ▸ CAPN10 ▸ LGALS1 ▸ PPARD ▸ WNT5A ▸
ACSL1 ▸ ADAMTS5 ▸ AQP8 ▸ F12 ▸ LGALS3 ▸ PVR ▸ BCAP31 ▸
PRKAR2A ▸ CAPN13 ▸ MCM7 ▸ IL1R2 ▸ CPP ▸ CYP1A1 ▸ ERP27 ▸
PRKAR2B ▸ MCOLN1 ▸ CAPN11 ▸ MTDH ▸ GPS2 ▸ PARP8 ▸ COPS5 ▸
ONECUT1 ▸ PCAF ▸ MID1 ▸ TAF1 ▸ SMARCD1 ▸ CREBBP ▸ RFX3 ▸
COPS2 ▸ NR3C1 ▸ UBC ▸ GTF2A1 ▸ BNC2 ▸ COPS4 ▸ TLX2 ▸
CDK4 ▸ GTF2E1 ▸ ZBTB3 ▸ GPS1 ▸ COPS6 ▸ GTF3A ▸ ARHGAP29 ▸
Data information
Please see the Gene Interactions Track Manual.