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IGF1 — RPTOR

Text-mined interactions from Literome

Roos et al., Am J Physiol Cell Physiol 2009 : We hypothesized that glucose, insulin, and IGF-I regulate placental amino acid transporters by inducing changes in mTOR signaling
Burgos et al., Domest Anim Endocrinol 2010 : In addition, IGF-1 stimulated mTORC1 kinase activity toward 4E-BP1 in vitro
Dennis et al., J Biol Chem 2013 : These findings were extended to a cell culture system wherein loss of 4E-BP1 and 4E-BP2 resulted in elevated interaction of p70S6K1 with IGF1 induced activation of mTORC1 in conjunction with an enhanced rate of p70S6K1 phosphorylation at Thr-389
Melnik et al., Hautarzt 2013 (Acne Vulgaris...) : mTORC1 , the central hub of protein- and lipid biosynthesis, cell growth and proliferation, is activated by insulin, IGF-1 and branched-chain essential amino acids, especially leucine ... mTORC1 , the central hub of protein- and lipid biosynthesis, cell growth and proliferation, is activated by insulin, IGF-1 and branched-chain essential amino acids, especially leucine
Ham et al., Exp Cell Res 2013 (Cardiomegaly...) : TRIM72 specifically regulated IGF-1 dependent AKT-mTOR signaling , resulting in a reduction of the size of cardiomyocytes