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CREB1 — IL10

Text-mined interactions from Literome

Leceta et al., Ann N Y Acad Sci 2000 (Inflammation) : VIP/PACAP inhibit iNOS expression through reduction in NFkB and IRF-1 binding, and augment IL-10 by increasing CREB binding
Gee et al., J Immunol 2007 : Furthermore, Tat induced IL-10 expression was regulated by p38 MAPK- and CaMK II-activated CREB-1 as well as Sp-1 transcription factors ... Taken together, our results suggest that extracellular HIV-Tat induced IL-10 transcription in primary human monocytes is regulated by CREB-1 and Sp-1 transcription factors through the activation of calmodulin/CaMK-II dependent p38 MAPK
Park et al., J Leukoc Biol 2008 : Further, overexpression of a dominant negative form of CREB suppressed gAcrp induced transcriptional activation of IL-10
Pongratz et al., Ann Rheum Dis 2012 (Arthritis, Experimental) : Interleukin 10 (IL-10) producing B cells suppress arthritis and are a potential target of the SNS because ( 1 ) B cells express functional ß ( 2 ) -adrenoceptors ( ß ( 2 ) ARs ) and ( 2 ) IL-10 , at least in monocytes/macrophages, is regulated in a cAMP/PKA/CREB dependent manner
Koscsó et al., J Immunol 2012 (MAP Kinase Signaling System) : Silencing CREB using lentivirally delivered short hairpin RNA blocked the enhancing effect of adenosine on IL-10 production, confirming a role for CREB in mediating the stimulatory effect of adenosine on IL-10 production
Nandan et al., J Immunol 2012 (Leishmaniasis, Visceral) : Infection of macrophages with leishmania induced phosphorylation of CREB at serine 133, and this was associated with enhanced CREB DNA binding activity and induction of IL-10
Ji et al., Liver Transpl 2012 (Disease Models, Animal...) : Liver protection due to cAMP-PKA stimulation was accompanied by diminished neutrophil and macrophage infiltration/activation, reduced hepatocyte necrosis/apoptosis, and increased cAMP response element binding protein ( CREB ) expression and augmented interleukin-10 (IL-10) expression
MacKenzie et al., J Immunol 2013 : However, although CREB regulates IL-10 transcription, the mutation of Ser ( 133 ) to Ala in the endogenous CREB gene did not prevent the ability of PGE ( 2 ) to promote IL-10 transcription
Elcombe et al., PloS one 2013 : Furthermore, we show that MSKs regulate dectin-1 induced IL-10 production, and that this regulation is dependent on the ability of MSKs to phosphorylate the transcription factor CREB
Wang et al., J Biol Chem 1995 : Several other transcription factors including NF-IL-6, AP-1, AP-2, GR, CREB , Oct-1, and Sp-1 are not affected by IL-10