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EPHB2 — TIE1

Text-mined interactions from Literome

Yoon et al., Biochem Biophys Res Commun 2003 : Localization of Tie2 and phospholipase D in endothelial caveolae is involved in angiopoietin-1 induced MEK/ERK phosphorylation and migration in endothelial cells
Tai et al., J Biol Chem 2005 : Tie2 and PECAM1 expression decreased > 80 % after siRNA treatment, and flow stimulated phosphorylation of ERK1/2 , Akt, and endothelial nitric oxide synthase was significantly inhibited by Tie2 and PECAM1 siRNA
Fukuhara et al., Nat Cell Biol 2008 : Furthermore, Tie2 activated at cell-cell or cell-substratum contacts leads to preferential activation of Akt and Erk , respectively
Yamakawa et al., J Biol Chem 2013 : When activation of Tie2YIA/LAS was induced by a high dose of Ang1, phosphorylation of Tie2 was limited compared with wild-type Tie2, resulting in retardation of activation of Erk downstream of Tie2