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RELA — TNFSF13B

Text-mined interactions from Literome

Yan et al., Nat Immunol 2000 : In vitro soluble TACI-Fc fusion protein blocked BLyS induced NF-kappa B activation in B lymphoma cells and IgM production in peripheral blood B cells
Shu et al., Proc Natl Acad Sci U S A 2000 : Overexpression of BCMA activates NF-kappaB , and this activation is potentiated by TALL-1
Claudio et al., Nat Immunol 2002 : We show here that B cell activating factor ( BAFF ) activates this second pathway and that this requires the BAFF receptor (BAFF-R), the NF-kappa B-inducing kinase (NIK) and protein synthesis, but not NEMO
Nishio et al., Blood 2005 (Leukemia, Lymphocytic, Chronic, B-Cell) : However, BAFF , but not APRIL, also induced CLL-cell activation of NF-kappaB2
Tai et al., Cancer Res 2006 (Bone Marrow Neoplasms...) : Adhesion of MM1S and MCCAR multiple myeloma cell lines to KM104 BMSC line transfected with a luciferase reporter vector carrying the BAFF gene promoter ( BAFF-LUC ) significantly enhanced luciferase activity, suggesting that nuclear factor-kappaB (NF-kappaB) activation induced by multiple myeloma adhesion to BMSCs mediates BAFF up-regulation
Kim et al., Blood 2008 (Lymphoma, Large B-Cell, Diffuse) : In addition, we show that NF-kappaB activation induced by B cell activating factor of tumor necrosis factor family ( BAFF ) in DLBCL cells requires PKK
Kuo et al., Blood 2008 (Lymphoma, B-Cell, Marginal Zone...) : In B-cell lymphoma Pfeiffer cells, BAFF activated NF-kappaB and AKT ; the activated NF-kappaB up-regulated BCL10, and the activated AKT caused formation of BCL10/BCL3 complexes that translocated to the nucleus
Li et al., Med Oncol 2010 (Multiple Myeloma) : Making use of the rhTACI-Fc to block the BAFF- and APRIL induced activation of NF-kappaB2 , we demonstrated that the NF-kappaB2-p52/RelB signal contributes to MM cell survival
Tusche et al., J Exp Med 2009 : We show that although MALT1 is largely dispensable for canonical NF-kappaB signaling downstream of the B cell receptor, the absence of MALT1 results in impaired BAFF induced phosphorylation of NF-kappaB2 ( p100 ), p100 degradation, and RelB nuclear translocation in B220 ( + ) B cells