Gene interactions and pathways from curated databases and text-mining

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IL15RA — RELA

Text-mined interactions from Literome

Pereno et al., Oncogene 2000 (Melanoma) : Thus, IL-15Ralpha controls NF-kappaB activation, however differences in the intracellular trafficking of the IL-15 and/or IL-15Ralpha suggest a different biological role for this complex in MELP versus MELREO cells
Mariner et al., J Immunol 2001 (Leukemia-Lymphoma, Adult T-Cell) : Furthermore, using promoter deletion constructs and gel shift analysis, we defined a functional NF-kappaB binding motif in the human IL-15Ralpha promoter, suggesting that Tax activation of IL-15Ralpha is due , in part, to the induction of NF-kappaB
Mariner et al., J Immunol 2002 : These findings suggest a role for both NF-kappaB and IRF-4 in the transcriptional regulation of IL-15Ralpha by HTLV-I Tax