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GTPBP4 — PGF

Text-mined interactions from Literome

Kozawa et al., Prostaglandins Leukot Essent Fatty Acids 1996 : We previously reported that prostaglandin F2 alpha ( PGF2 alpha ) activates phosphatidylcholine hydrolyzing phospholipase D independently from the activation of protein kinase C ( PKC ) in osteoblast-like MC3T3-E1 cells, and reported that pertussis toxin-sensitive GTP binding protein ( G-protein ) is involved in the PGF2 alpha induced phospholipase D activation
Tokuda et al., J Cell Biochem 1998 : In previous studies, we have reported that PGF2alpha stimulates phosphoinositide hydrolysis by phospholipase C and phosphatidylcholine hydrolysis by phospholipase D through heterotrimeric GTP binding protein in osteoblast-like MC3T3-E1 cells, and that PGF2alpha and PGE1 induce interleukin-6 (IL-6) synthesis via activation of protein kinase C and protein kinase A, respectively