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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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MLST8 — PAM

Text-mined interactions from Literome

Han et al., Cell Signal 2008 (Tuberous Sclerosis) : Pam ( Protein associated with Myc ) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling
Han et al., J Biol Chem 2012 : Our results establish that Pam regulates TSC/mTOR signaling in vitro and in vivo through two distinct domains
Bahl et al., Molecular autism 2013 : Pam , an E3 ubiquitin ligase, binds to TSC proteins and regulates mTORC1 signaling in the CNS, and the FBXO45-Pam ubiquitin ligase complex plays an essential role in neurodevelopment by regulating synapse formation and growth