Gene interactions and pathways from curated databases and text-mining

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CCR3 — IL5

Text-mined interactions from Literome

Stirling et al., Am J Respir Crit Care Med 2001 (Asthma) : Interleukin-5 induces CD34 ( + ) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma ... Intravenous IL-5 increased mature eosinophil CCR3 expression from a baseline mean fluorescence intensity ( MFI ) of 658 +/- 51.7 to 995 +/- 93.2 at 24 h ( p < 0.05 ), but had no effect on interleukin-5 receptor subunit alpha or CD11b expression
Gregory et al., J Immunol 2003 : CCR3 expression was down-regulated by IL-3 and was transiently reduced by IL-5 and GM-CSF, but rapidly returned toward baseline
Catley et al., IDrugs 2010 (Asthma...) : This conference report highlights selected presentations on mAb treatments for asthma, including targeting IL-5 , IL-13, IL-9 and TNFa, CCR3 inhibitors , histamine H4 receptor inhibition, novel mouse models of COPD and inhaled antisense asthma therapies ... This conference report highlights selected presentations on mAb treatments for asthma, including targeting IL-5 , IL-13, IL-9 and TNFa, CCR3 inhibitors , histamine H4 receptor inhibition, novel mouse models of COPD and inhaled antisense asthma therapies
Wang et al., Thorax 2013 (Asthma...) : However, CCR8 inhibition had no significant effect on allergen induced BAL eosinophilia and the induction of the Th2 cytokines IL-4, IL-5 , IL-13 and mucus levels in BAL
Tiffany et al., J Immunol 1998 : CCR3 was expressed later and at lower levels than CCR1 and could be further induced by IL-5 , whereas IL-5 had little or no effect on CCR1 expression