Gene interactions and pathways from curated databases and text-mining

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CLU — IGF1

Text-mined interactions from Literome

Goetz et al., Oncogene 2011 (Genomic Instability...) : ATM dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability
Chesnokova et al., Mol Endocrinol 2012 (Chromosomal Instability...) : FOXL2 directly stimulates the Clu gene promoter, and we show that PTTG triggers ataxia telangiectasia mutated kinase/IGF-I/p38MAPK DNA damage/chromosomal instability signaling, which in turn also induces Clu expression
Laping et al., J Am Soc Nephrol 1997 : Epidermal growth factor, insulin-like growth factor-1 , and transforming growth factor-beta 1 had little or no effect on clusterin mRNA levels