Gene interactions and pathways from curated databases and text-mining

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EGR1 — HOXA5

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: EGR1 → HOXA5 (increases, EGR1 Activity) Chen et al., J Biol Chem 2005*
    Evidence: Supplementary Table 3 and 4 - Up-regulated and down-regulated genes at 9 h post induction of HOXA5 in Hs578T breast cancer cell line (GEO2241)
  • OpenBEL Selventa BEL large corpus: EGR1 → HOXA5 (increases, EGR1 Activity) Chen et al., J Biol Chem 2005*
    Evidence: In order to decipher downstream signaling pathways of HOXA5, we utilized oligonucleotide microarray analysis to identify genes that are differentially expressed in HOXA5-induced cells compared with uninduced cells.