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ILK — MMP9

Text-mined interactions from Literome

Troussard et al., Oncogene 2000 (Glioblastoma) : Transient transfection of wild-type GSK-3beta in ILK overexpressing cells decreased MMP-9 promoter activity and AP-1 activity, indicating that ILK can stimulate MMP-9 expression via GSK-3beta and AP-1 transcription factor ... Furthermore, both MMP-9 promoter and AP-1 activities were inhibited by the ILK inhibitor
von Lüttichau et al., Biol Chem 2002 : A synthetic ILK inhibitor blocked MMP-9 mRNA upregulation but showed no effect on TIMP-1 or MMP-2 mRNA expression
Kang et al., Kidney Int 2010 (Proteinuria) : In vivo, this ILK inhibitor ameliorated albuminuria, repressed glomerular induction of MMP-9 and alpha-SMA, and preserved nephrin expression in murine adriamycin nephropathy
Zhao et al., International journal of medical sciences 2013 : In the present study, we found that overexpression of ILK stimulated matrix metalloproteinase-9 (MMP-9) expression and activity in lung cancer cells