Gene interactions and pathways from curated databases and text-mining

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STAT3 — ZFP36

Text-mined interactions from Literome

Schaljo et al., J Immunol 2009 (Inflammation) : We found that IL-10 initiates a Stat3 dependent increase of TTP expression accompanied by a delayed decrease of p38 MAPK activity
Joe et al., J Biol Chem 2011 (Inflammation) : Nicotine induced activation of STAT3 enhanced STAT3 binding to the TTP promoter, increased TTP promoter activity, and increased TTP expression resulting in the suppression of LPS stimulated TNF-a production
Gaba et al., J Immunol 2012 : Correspondingly, STAT3 was required for efficient IL-10 induced TTP expression ... Hence, by inducing TTP expression, STAT3 activates a negative regulatory loop that controls the IL-10/STAT3 anti-inflammatory response