Gene interactions and pathways from curated databases and text-mining

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AKT1 — TNFSF13B

Text-mined interactions from Literome

Kuo et al., Blood 2008 (Lymphoma, B-Cell, Marginal Zone...) : In B-cell lymphoma Pfeiffer cells, BAFF activated NF-kappaB and AKT ; the activated NF-kappaB up-regulated BCL10, and the activated AKT caused formation of BCL10/BCL3 complexes that translocated to the nucleus ... Inhibition of AKT by LY294002 ( a PI3K inhibitor ) blocked BCL10 nuclear translocation, NF-kappaB transactivity, and BAFF expression
Otipoby et al., Proc Natl Acad Sci U S A 2008 : BAFF activates Akt and Erk through BAFF-R in an IKK1 dependent manner in primary mouse B cells
Li et al., J Ethnopharmacol 2012 (Arthritis, Experimental) : To investigate the role of PI3K/Akt/mTOR signaling mediated by BAFF/BAFF-R in antibodies production and the regulation of Pae on the signaling pathway in rats with collagen induced arthritis ( CIA ) ... PI3K/Akt/mTOR signaling mediated by BAFF/BAFF-R participates in antibodies production by B lymphocytes of CIA rats
Zhang et al., PloS one 2012 : In contrast, RhoA deficiency led to a defect in B cell activating factor ( BAFF ) -mediated B cell survival that was associated with a dampened expression of BAFF receptor and a loss of BAFF mediated Akt activation
Zhu et al., J Exp Clin Cancer Res 2012 (Breast Neoplasms) : We also found that the number of migrated cells was increased in the presence of BLyS and inhibition of phosphorylation of Akt attenuated the enhanced migratory response
Liu et al., Eur J Pharmacol 2012 (Arthritis, Experimental) : To investigate the role of PI3K/Akt/mTOR signaling mediated by B cell activating factor belonging to the TNF family ( BAFF ) involved in anti-apoptosis of B lymphocytes in rats with collagen induced arthritis ( CIA ) and the regulation of epigallo-catechin-3-gallate ( EGCG )