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CHUK — ROCK1

Text-mined interactions from Literome

Wei et al., Mol Pharmacol 2006 : Further studies showed that LPS down-regulated Rho and ROCK activity, whereas IL-1beta increased them, suggesting a negative role of Rho and ROCK signaling, which is regulated in contrary manners by IL-1beta and LPS, in IKK/NF-kappaB activation
Rafferty et al., Cell Immunol 2012 : ROCK inhibition also suppressed IL-1 induced JNK phosphorylation in both cell lines, but high levels of the inhibitor had no significant effect on IL-1 stimulated Caco-2 I?Ba phosphorylation and degradation or IKK phosphorylation and kinase activity