Gene interactions and pathways from curated databases and text-mining

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CREB1 — PPARG

Text-mined interactions from Literome

Herzig et al., Nature 2003 (Fatty Liver) : The coordinate induction of PGC-1 and repression of PPAR-gamma by CREB during fasting provides a molecular rationale for the antagonism between insulin and counter-regulatory hormones, and indicates a potential role for CREB antagonists as therapeutic agents in enhancing insulin sensitivity in the liver
Fox et al., J Biol Chem 2006 : Loss of CREB/ATF1 prevented the expression of PPARgamma , C/EBP alpha, and adiponectin and inhibited the loss of Pref-1 ... Finally results are presented showing that CREB promotes PPARgamma2 gene transcription