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PIAS1 — STAT3

Pathways - manually collected, often from reviews:

• KEGG Jak-STAT signaling pathway: PIAS1/PIAS2/PIAS3/PIAS4 → STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 (protein-protein, inhibition)
  

Text-mined interactions from Literome

Levy et al., Blood 2006 : This motif ( PIAS82-132 ), which contains 50 amino acids, is sufficient for the inhibition of both MITF and STAT3
Brantley et al., Clin Cancer Res 2008 (Glioblastoma) : Conversely, PIAS3 overexpression inhibited STAT-3 transcriptional activity, expression of STAT-3 regulated genes, and cell proliferation