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PCNA — STAT3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Matsui et al., J Biol Chem 2002
:
Thus,
STAT3 mediated down-regulation of
cyclin D expression is rather specific to fetal hepatocytes that are undergoing maturation processes including a reduction of their proliferation potential
Yoshida et al., J Exp Med 2002
(Cell Transformation, Neoplastic...) :
Activation of
STAT3 by the HCV core in NIH-3T3 cells
resulted in rapid proliferation and up-regulation of Bcl-XL and
cyclin-D1
Siejka et al., Prostate 2010
(Prostatic Hyperplasia) :
We also measured by Western blot the influence of GHRH and GHRH antagonist JMR-132 on the expression of the
PCNA and the
activation of ERK1/2 and
JAK/STAT3
Takaishi et al., Cancer Sci 2010
(Ascites...) :
Blocking of Stat3 in macrophages by small interfering RNA inhibited the production of IL-6 and IL-10 by macrophages, and suppressed
Stat3 activation and
cyclin-D1 induction in co-cultured SKOV3 cells
Ray et al., J Invest Dermatol 2013
(Cicatrix, Hypertrophic) :
The cellular proliferation markers
Cyclin D1, Bcl-Xl, and c-Myc were also upregulated in HSF, and knockdown of STAT3 by small interfering RNA attenuated c-Myc expression indicating the
essential role of
STAT3 in fibroblast proliferation