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IGF2 — PAPSS1

Text-mined interactions from Literome

El-Shewy et al., Mol Endocrinol 2011 : Pretreating cells with protein kinase C ( PKC ) inhibitor, bisindolylmaleimide-I, abolished IGF-II stimulated translocation of green fluorescent protein ( GFP ) -tagged SK1 to the plasma membrane and activation of endogenous SK1 , implicating PKC as an upstream regulator of SK1 ... Taken together, these data provide evidence that activation of PLC and PKCß2 by the IGF-II/M6P receptor are required for the activation of SK1
Bernacchioni et al., Skeletal muscle 2012 : The effect of the growth factor does not involve transcriptional regulation of SK1 or SK2, since the protein content of both isoforms is not affected ; rather, IGF-1 enhances the fraction of the active form of SK