Gene interactions and pathways from curated databases and text-mining

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MAPK3 — P2RY2

Text-mined interactions from Literome

Gao et al., J Biol Chem 1999 : A2B adenosine and P2Y2 receptors stimulate mitogen activated protein kinase in human embryonic kidney-293 cells
Liu et al., J Biol Chem 2004 (Astrocytoma) : A mutant P2Y(2) receptor lacking the PXXP motifs was found to stimulate calcium mobilization and serine/threonine phosphorylation of the Erk1/2 mitogen activated protein kinases, like the wild-type receptor, but was defective in its ability to stimulate tyrosine phosphorylation of Src and Src dependent tyrosine phosphorylation of the proline-rich tyrosine kinase 2, epidermal growth factor receptor (EGFR), and platelet derived growth factor receptor
Morris et al., Am J Physiol Cell Physiol 2012 (Hypertension) : These data highlight a differential arrestin dependent regulation of ET ( A ) and P2Y(2) receptor stimulated MAPK signaling
Patel et al., Biochem J 1996 : 2-Methylthio-ATP and UTP, selectively activating P2Y1 and P2Y2 purinoceptors respectively, and ATP, a non-selective agonist at these two receptors, stimulate the tyrosine phosphorylation of both p42mapk and p44mapk , as revealed by Western blots with an antiserum specific for the tyrosine phosphorylated forms of the enzymes
Soltoff et al., J Biol Chem 1998 : Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen activated protein kinase by the G-protein coupled P2Y2 receptor