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MAPK3 — P2RY2
Text-mined interactions from Literome
Gao et al., J Biol Chem 1999
:
A2B adenosine and
P2Y2 receptors
stimulate mitogen activated protein kinase in human embryonic kidney-293 cells
Liu et al., J Biol Chem 2004
(Astrocytoma) :
A mutant
P2Y(2) receptor lacking the PXXP motifs was found to stimulate calcium mobilization and serine/threonine phosphorylation of the
Erk1/2 mitogen
activated protein kinases, like the wild-type receptor, but was defective in its ability to stimulate tyrosine phosphorylation of Src and Src dependent tyrosine phosphorylation of the proline-rich tyrosine kinase 2, epidermal growth factor receptor (EGFR), and platelet derived growth factor receptor
Morris et al., Am J Physiol Cell Physiol 2012
(Hypertension) :
These data highlight a differential arrestin dependent regulation of ET ( A ) and
P2Y(2) receptor
stimulated MAPK signaling
Patel et al., Biochem J 1996
:
2-Methylthio-ATP and UTP, selectively activating P2Y1 and
P2Y2 purinoceptors respectively, and ATP, a non-selective agonist at these two receptors,
stimulate the tyrosine phosphorylation of both p42mapk and
p44mapk , as revealed by Western blots with an antiserum specific for the tyrosine phosphorylated forms of the enzymes
Soltoff et al., J Biol Chem 1998
:
Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the
stimulation of
mitogen activated protein kinase by the G-protein coupled
P2Y2 receptor