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AKT1 — NTS

Text-mined interactions from Literome

Egea et al., J Cell Biol 2001 : In this report, we have analyzed the involvement of Ca2+ and calmodulin (CaM) in the activation of the PKB induced by NTs
Martin et al., J Neurosci Res 2005 : In the murine microglial cell line N11, the neurotensin receptor-3 is also the only neurotensin receptor expressed, and its activation by neurotensin leads to the phosphorylation of both Erk1/2 and Akt
Müller et al., BMC cancer 2011 (Colonic Neoplasms...) : In Panc-1 cells, neurotensin induced phosphorylation of ERK, but not Akt , was dependent on protein kinase C ( PKC ), whereas an inhibitor of the ß-isoform of phosphoinositide 3-kinase (PI3K), TGX221, abolished neurotensin induced Akt phosphorylation in these cells, and there was no evidence of EGF receptor (EGFR) transactivation ... In HT29 cells, in contrast, the EGFR tyrosine kinase inhibitor gefitinib blocked neurotensin stimulated phosphorylation of both ERK and Akt , indicating transactivation of EGFR, independently of PKC