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NOS1 — NPY
Text-mined interactions from Literome
Morley et al., Peptides 1999
(Body Weight) :
This study examined the
effects of
NPY and leptin on
nitric oxide synthase (NOS) in the hypothalamus ...
NPY at the lower dose
increased NOS in the hypothalamus by 147 %
Kolo et al., Am J Physiol Heart Circ Physiol 2004
(Hypertension...) :
In contrast to what was observed in the isolated perfused mesenteric arterial bed obtained from normotensive animals, inhibition of
NOS did not
result in a further increase in the overflow of norepinephrine or in a subsequent decrease in
NPY
Chandrasekharan et al., PloS one 2008
(Colitis...) :
The lower histological scores, MPO and chemokine KC in S.T. treated nNOS ( -/- ) and NPY ( -/- ) /nNOS ( -/- ) mice supported the finding that loss of
NPY induced
nNOS attenuated inflammation ...
NPY mediated increase in
nNOS is a determinant of oxidative stress and subsequent inflammation
Lian et al., Sheng Li Xue Bao 2010
:
Intrahippocampal microinjections of
NPY , NPY-Y1 receptor antagonist GR231118 and non-specific
NOS inhibitor N-nitro-L-arginine methyl ester ( L-NAME ) were respectively adopted by rat brain stereotaxic coordinates