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HIF1A — NOS1

Text-mined interactions from Literome

Hu et al., Chin Med J (Engl) 2002 (Anoxia...) : Hypoxia-inducible factor 1 alpha upregulates the expression of inducible nitric oxide synthase gene in pulmonary arteries of hyposic rat
Wang et al., Bone 2004 : Human osteoblasts were treated with or without US stimulation ( 200 micros pulse, 1 kHz at 30 mW/cm2 ) for 20 min. Cells were subjected to assessment of VEGF-A expression, NO production, nitric oxide synthase (NOS) catalytic activities, and HIF-1alpha transactivation ... Human osteoblasts were treated with or without US stimulation ( 200 micros pulse, 1 kHz at 30 mW/cm2 ) for 20 min. Cells were subjected to assessment of VEGF-A expression, NO production, nitric oxide synthase (NOS) catalytic activities, and HIF-1alpha transactivation ... Inhibition of NOS activity by N-nitro-L-arginine methyl ester ( L-NAME ) or blockade of guanylate cyclase activity by ODQ reduced US-augmented HIF-1alpha transactivation and VEGF-A levels
Brennan et al., Ann R Coll Surg Engl 2005 (Carcinoma, Squamous Cell...) : Three oral cancer cell lines were used to investigate the effects of NO synthase enzymes (NOS) on HIF-1alpha expression under both normal oxygen and hypoxic conditions
Quintero et al., Cancer Res 2006 (Carcinoma, Squamous Cell...) : Furthermore, in three human cell lines derived from human oral squamous cell carcinoma, the accumulation of HIF-1alpha was prevented either by inhibition of NOS activity with the nonspecific NOS inhibitor N ( G ) -monomethyl-L-arginine or by the antioxidants N-acetyl-L-cysteine and ascorbic acid
Li et al., Circ Res 2008 (Disease Models, Animal...) : Two weeks after ODN transfection, the HIF-1alpha binding activities were significantly inhibited by 45 %, and high salt induced increases of nitric oxide synthase-2 and heme oxygenase-1 transcriptions were also inhibited by 70 % and 61 % in the renal medulla from decoy rats