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AKT1 — MATK

Text-mined interactions from Literome

Sampath et al., Blood 2006 (Blast Crisis...) : However, inhibition of Chk1 by UCN-01 in S-phase arrested cells resulted in an abrogation of the checkpoint, inhibition of Akt , activation of JNK, and a rapid induction of apoptosis
Kuo et al., Mol Cancer Ther 2006 (Breast Neoplasms) : Furthermore, suppression of AKT by plumbagin enhanced the activation of Chk2 , resulting in increased inactive phosphorylation of Cdc25C and Cdc2
Tonic et al., J Biol Chem 2010 : Akt prevents the translocation of BRCA1 to DNA damage foci and, thereby, inhibiting the activation of Chk1 following DNA damage