Gene interactions and pathways from curated databases and text-mining

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KITLG — STAT3

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Duarte et al., Blood 2000 : G-CSF, but not SCF , induces the tyrosine phosphorylation of STAT1 and STAT3 , transcription factors that can mediate the induction of c-fos
Shivakrupa et al., Cell Signal 2005 : In this study, we used Lyn-deficient bone marrow mast cells ( BMMC ) to examine the contribution of this Src family member to tyrosine phosphorylation of Kit and SCF induced activation of Jnks, Akt, Stat3 and Erks ... Further, Lyn was required for SCF induced tyrosine phosphorylation of Stat3 ... These data indicate that in BMMC, Lyn contributes to SCF induced phosphorylation of Kit, as well as phosphorylation of Jnks and Stat3