Gene interactions and pathways from curated databases and text-mining

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ITGA4 — MAPK3

Text-mined interactions from Literome

Geutskens et al., Eur J Immunol 2004 (Inflammation) : Moreover, the mitogen activated protein kinase extracellular signal regulated kinase-1/2 negatively regulated macrophage CD49d expression and strongly suppressed its expression in NOD macrophages
Bauer et al., J Biol Chem 2006 (Melanoma) : We found that MIA interacts with integrin alpha4beta1 and alpha5beta1, leading to down-regulation of integrin activity and reduction of mitogen activated protein kinase signaling