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IL5 — STAT3
Text-mined interactions from Literome
O'Brien et al., J Biol Chem 1999
:
STAT3 activation in stromal/osteoblastic cells is
required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130 utilizing cytokines or
interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone
Nielsen et al., Blood 2002
(Lymphoma, T-Cell, Cutaneous) :
Spontaneous
interleukin-5 production in cutaneous T-cell lymphoma lines is
mediated by constitutively activated
Stat3
Stout et al., J Immunol 2004
:
IL-5 and granulocyte-macrophage colony stimulating factor
activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils
Ozawa et al., Journal of ophthalmology 2011
:
In innate chorioretinal inflammation,
interleukin-6 family ligands
induce STAT3 activation in photoreceptors, which causes UPS mediated excessive degradation of the visual substance, rhodopsin
Caldenhoven et al., J Biol Chem 1995
(Acute-Phase Reaction) :
Activation of the
STAT3/acute phase response factor transcription factor by
interleukin-5 ... We found that
IL-5 induces binding of
STAT3 to the intercellular adhesion molecule-1 pIRE, and activates STAT3 dependent transcription