Gene interactions and pathways from curated databases and text-mining

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IL5 — STAT3

Text-mined interactions from Literome

O'Brien et al., J Biol Chem 1999 : STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130 utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone
Nielsen et al., Blood 2002 (Lymphoma, T-Cell, Cutaneous) : Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
Stout et al., J Immunol 2004 : IL-5 and granulocyte-macrophage colony stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils
Ozawa et al., Journal of ophthalmology 2011 : In innate chorioretinal inflammation, interleukin-6 family ligands induce STAT3 activation in photoreceptors, which causes UPS mediated excessive degradation of the visual substance, rhodopsin
Caldenhoven et al., J Biol Chem 1995 (Acute-Phase Reaction) : Activation of the STAT3/acute phase response factor transcription factor by interleukin-5 ... We found that IL-5 induces binding of STAT3 to the intercellular adhesion molecule-1 pIRE, and activates STAT3 dependent transcription