Gene interactions and pathways from curated databases and text-mining

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IL2RA — IL5

Text-mined interactions from Literome

Chihara et al., Eur Cytokine Netw 1992 : Induction of CD23, CD25 and CD4 expression on an eosinophilic cell line ( EoL-3 ) by interleukin-3 (IL-3), granulocyte-macrophage colony stimulating factor ( GM-CSF ) and interleukin-5 (IL-5) ... The effects of IL-3, GM-CSF and IL-5 on the expression of CD23 ( Fc epsilon RII ), CD25 ( IL-2R/p55 ) and CD4 on an eosinophilic cell line ( EoL-3 ) were investigated by flow cytometry
Tchórzewski et al., Med Sci Monit 2005 (Autoimmune Diseases...) : We analyzed reactive oxygen intermediate ( ROI ) production by peripheral blood granulocytes, the production of IL-2, IL-5 , IL-10, IL-12, and TNF-alpha cytokines by lymphocytes, and the activation of CD25 , CD26, CD69, CD71, and HLA DR antigen expression
Benghiat et al., Transplantation 2005 : Finally, natural CD25 ( + ) Treg cells inhibited the production of interleukin (IL)-2, interferon-gamma, IL-5 , and IL-13 in mixed lymphocyte culture in a dose dependent manner
Leech et al., J Immunol 2007 (Asthma...) : Most convincingly, transfer of CD4 ( + ) CD25 ( + ) Foxp3 ( + ) T cells from Ag naive mice ( natural Tregs ) abolished AAI, decreased dMLN IL-5 and IL-13 secretion, increased dMLN IL-10 secretion, abolished IgE, and decreased IgG1 Abs. Blocking IL-10 receptor function in vivo did not block the anti-inflammatory function of transferred natural Tregs but did restore dMLN IL-5 and IL-13 secretion
Zhao et al., Leukemia 2008 (Hypersensitivity, Delayed) : sorafenib also caused G ( 0 ) /G ( 1 ) phase arrest, inhibition of CD25 and CD69 expression, interleukin-2 production and LCK phosphorylation in the T cells ; all of these effects exhibited dose and time dependence
Verma et al., Blood 2009 : CD4 ( + ) CD25 ( + ) T cells from tolerant hosts given IL-2 cultured cells had increased Il-5 and Ifngammar mRNA
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Shirakawa et al., Mol Cell Biol 1989 : Identical results were obtained with the human natural killer-like cell line YT, which can be induced to express the interleukin-2 receptor alpha subunit in response to interleukin-1 , cyclic AMP, or phorbol 12-myristate 13-acetate
Chihara et al., Nihon rinsho. Japanese journal of clinical medicine 1993 : The effects of IL-3, GM-CSF and IL-5 on the expression of CD23 ( Fc ( E ) RII ), CD25 ( IL-2R/p55 ) and CD4 on an eosinophilic cell line ( EoL-3 ) were investigated by flow cytometry