Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF1

IGF1 — IL10

Text-mined interactions from Literome

Stearns et al., Clin Cancer Res 2003 (Prostatic Neoplasms) : Northern blots, Western blots, and ELISAs showed that IL-10 suppressed IGF-I induction of MMP-2 and MT1-MMP mRNA synthesis in these cell strains ( P < 0.001 ) ... The data show that IL-10 blocks IGF-I activation of MMP-2 and MT1-MMP mRNA expression and protein synthesis in primary prostate cell strains
Kooijman et al., J Leukoc Biol 2004 : Insulin-like growth factor-I stimulates IL-10 production in human T cells ... We found that IGF-I stimulated the secretion of the Th2 cytokine interleukin (IL)-10 by 40-70 % in PHA stimulated PBMC ... IL-10 secretion was also stimulated in purified T cells, and we established that IGF-I also stimulated IL-10 mRNA expression by 100-150 % ... The monocyte activating bacterial cell-wall product lipopolysaccharide induced IL-10 production in PBMC, but this was not affected by IGF-I
Méndez-Dávila et al., J Endocrinol Invest 2004 (Osteoporosis) : We investigated the effects of 17betaestradiol and two selective estrogen receptor modulators, tamoxifen and raloxifene, on the expression and release of constitutive and interleukin-1 stimulated interleukin (IL)-6, transforming growth factor-beta1 ( TGF-beta1 ) and insulin-like growth factor-1 by osteoblasts in primary culture from trabecular bone of healthy post-menopausal women
Glazebrook et al., J Vasc Res 1998 : Regulation of insulin-like growth factor-1 expression in vascular endothelial cells by the inflammatory cytokine interleukin-1