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IDO1 — TLR4

Text-mined interactions from Literome

Opitz et al., Stem Cells 2009 : Induction of IDO1 by TLR involved an autocrine interferon (IFN)-beta signaling loop, which was dependent on protein kinase R (PKR), but independent of IFN-gamma
Park et al., Exp Mol Med 2011 (Arthritis, Rheumatoid) : Surprisingly, toll-like receptor (TLR)4 mediated IDO expression was upregulated after depletion of myeloid differentiation primary response protein 88 ( MyD88 ) in synovial fibroblasts using small interfering RNA ( siRNA ) ... These data suggest that upregulation of IDO expression in synovial fibroblasts involves TLR3 and TLR4 activation by microbial constituents
Lei et al., J Med Primatol 2013 : Toll-like receptor ( TLR ) stimulation significantly increased IDO protein level in CD14 ( + ), CD56 ( + ), CD1c ( + ), CD11c ( + ), and CD123 ( + ) myeloid cells