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HDAC1 — WNT11
Text-mined interactions from Literome
Smith et al., J Biol Chem 2005
:
These results suggest that inhibition of a PI3K/Akt/GSK3beta/beta-catenin/LEF axis and stimulation of
HDAC1 cooperate to
mediate the inhibitory effect of DEX on
Wnt signaling and the osteoblast differentiation related cell cycle
Yamaguchi et al., Development 2005
:
Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing
Wnt and Notch signaling pathways
Sierra et al., Genes Dev 2006
:
We conclude that, in addition to regulating the stability of beta-cat, APC facilitates
CtBP mediated repression of
Wnt target genes in normal, but not in colorectal cancer cells
Liu et al., Biochim Biophys Acta 2009
:
Our data suggest that
WNT signaling pathway plays important
roles in the regulation of
Hdac1 during the early stage of cardiomyocyte differentiation and that the downregulation of Hdac1 promotes cardiac differentiation
Debeb et al., Stem Cells 2012
(Breast Neoplasms...) :
Moreover, while
HDAC inhibitors upregulated ß-catenin expression and significantly
increased WNT reporter activity, a TCF4 dominant negative construct abolished HDAC-inhibitor induced expansion of CSCs
Aldiri et al., Development 2013
(Wnt Signaling Pathway) :
We also show that
Wnt/ß-catenin signaling acting through the receptor Frizzled 5, but independent of Sox2,
regulates expression of key
PRC2 subunits in the developing retina