◀ Back to AKT1
AKT1 — GRM1
Text-mined interactions from Literome
Shin et al., Pigment Cell Melanoma Res 2010
(Cell Transformation, Neoplastic...) :
In cultured stable Grm1-mouse-melanocytic clones, as well as an metabotropic glutamate receptor 1 ( Grm1 ) expressing human melanoma cell line, C8161, stimulation of Grm1 by its agonist led to the activation of AKT, while preincubation with Grm1-antagonist abolished
Grm1-agonist induced
AKT activation
Ribeiro et al., J Neurosci 2010
(Disease Models, Animal...) :
Furthermore,
mGluR1/5 stimulated
AKT and extracellular signal regulated kinase ( ERK ) activation is altered in Hdh ( Q111/Q111 ) mice
Wangari-Talbot et al., Mol Cancer Res 2012
(MAP Kinase Signaling System...) :
We showed that suppression of
GRM1 expression in several human melanoma cell lines
resulted in a reduction in the number of viable cells and a decrease in stimulated mitogen activated protein kinase ( MAPK ) and
PI3K/AKT and suppressed tumor progression in vivo