Gene interactions and pathways from curated databases and text-mining

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GH1 — NPY

Text-mined interactions from Literome

Rettori et al., Endocrinology 1990 : Physiologically significant effect of neuropeptide Y to suppress growth hormone release by stimulating somatostatin discharge
Peng et al., Neuroendocrinology 1990 : The effects of neuropeptide Y (NPY) on release of growth hormone (GH) and gonadotropin ( GTH ) from the goldfish pituitary in vitro were investigated
Williams et al., Diabetes 1989 (Diabetes Mellitus, Experimental) : Because both of these regions are important in modulating pituitary hormone secretion, local NPY increases may be involved in the impaired secretion of luteinizing hormone, thyroid stimulating hormone, growth hormone , and prolactin known to occur in STZ-D
Chabot et al., Neuroendocrinology 1988 : In vitro studies using dispersed anterior pituitary cells indicated that NPY ( 10 ( -6 ) to 10 ( -9 ) M ) increased the secretion of luteinizing hormone, growth hormone and prolactin, whereas beta-lipotropin hormone and thyrotropin secretions were not affected
Härfstrand et al., Regul Pept 1987 : NPY ( 250-750 pmol ) reduced the serum levels of thyreotropine ( TSH ), prolactin (PRL) and growth hormone (GH) but increased CORTICO, adrenocorticotropin ( ACTH ) and ALDO serum levels
McDonald et al., Proc Natl Acad Sci U S A 1985 : NPY ( 10 ( -6 ) and 10 ( -7 ) M ) stimulated secretion of LH, growth hormone , and follicle stimulating hormone from perifused anterior pituitary cells loaded in a Bio-Gel P-2 column ... These results indicate that NPY acts on structures adjacent to the third ventricle to inhibit the secretion of LH and growth hormone but not follicle stimulating hormone, whereas it can directly stimulate the secretion of all three hormones from the cells of the anterior pituitary in vitro
Peng et al., Gen Comp Endocrinol 1993 : In the present study, we used synthetic gNPY to investigate the role of NPY in the regulation of growth hormone (GH) and gonadotropin-II ( GtH-II ) in the goldfish
Suzuki et al., Regul Pept 1996 : Inhibitory effect of neuropeptide Y on growth hormone secretion in rats is mediated by both Y1- and Y2-receptor subtypes and abolished after anterolateral deafferentation of the medial basal hypothalamus ... Neuropeptide Y (NPY) may play a physiological role in the regulation of growth hormone (GH) secretion by acting via somatostatin (SS) in the periventricular nucleus ( PeV ), as well as via the GH-releasing factor in the arcuate nucleus (ARC) of the medial basal hypothalamus ( MBH )
Watanobe et al., Neuropeptides 1996 (Pituitary Neoplasms...) : Stimulation by neuropeptide Y of growth hormone secretion in prolactinoma in vivo
Watanobe et al., Neuropeptides 1997 (Acromegaly) : Stimulatory and inhibitory effects of neuropeptide Y on growth hormone secretion in acromegaly in vivo ... It has been reported that neuropeptide Y (NPY) affects growth hormone (GH) secretion in several animal species