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FOXP3 — TLR4
Text-mined interactions from Literome
Bell et al., J Immunol 2007
:
We hypothesized that the transcription factor
forkhead box P3 (FOXP3) regulates the expression of
TLR family members in human Treg cells
Piconi et al., AIDS 2010
(HIV Infections) :
Activated T cells ( Ki67 ( + ) ), Treg lymphocytes ( CD4 ( + )
/CD25high/Foxp3+ ), divided into naive and activated cells based on PD1 expression, interleukin (IL)-10 and transforming growth factor ( TGF ) -beta production, annexin V,
activation of caspases 8 and 9,
Toll-like receptor (TLR)2 and TLR4 expression on immune cells, and plasma lipopolysaccharide (LPS) concentration were analyzed
de Kivit et al., Immunobiology 2011
(Inflammation) :
TLR4 ligation of IEC ( HT-29 )
enhanced the production of TNF-a and IEC derived MDC and decreased numbers of
Foxp3 ( + ) regulatory T cells
Jia et al., Mol Med Report 2012
:
Foxp3 expression in A549 cells is
regulated by
Toll-like receptor 4 through nuclear factor-?B ... We hypothesised that
TLR4 may also be
involved in the regulation of
Foxp3 in A549 cells through NF-?B ... Therefore, we examined the
effect of
TLR4 and NF-?B on the expression of
Foxp3 in the A549 lung cancer cell line ... These results suggest that
TLR4 is
involved in the regulation of
Foxp3 in A549 cells through NF-?B