Gene interactions and pathways from curated databases and text-mining

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F12 — HIF1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Koh et al., Mol Cell Biol 2008 (Neoplasms, Experimental...) : Furthermore, HAF overexpression decreases HIF-1alpha levels in normoxia and hypoxia in both pVHL-competent and -deficient cells, whereas HAF knockdown increases HIF-1alpha levels in normoxia, hypoxia, and under epidermal growth factor stimulation
Koh et al., Cell cycle (Georgetown, Tex.) 2009 (Neoplasms) : Here we summarize the mechanism of HAF mediated HIF-1alpha degradation and the importance of oxygen independent HIF-1alpha regulation in cancer