Gene interactions and pathways from curated databases and text-mining

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EGFR — TLR4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Fukata et al., Gastroenterology 2007 (Chronic Disease...) : Mechanistically, we show that TLR4 is responsible for induction of Cox-2, increased prostaglandin E ( 2 ) production, and activation of EGFR signaling in chronic colitis
Basu et al., J Biol Chem 2008 (Stomach Neoplasms) : Disruption of lipid rafts with methyl beta-cyclodextrin prevents HP0175 induced tyrosine phosphorylation of TLR4 and activation of EGFR