Gene interactions and pathways from curated databases and text-mining

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EDN1 — IL5

Text-mined interactions from Literome

Fujisawa et al., J Asthma 2002 : Theophylline inhibited IL-5 induced release of EDN in a concentration dependent manner
Sharmin et al., Inflamm Res 2002 : ET-1 ( 1-31 ) and a 21-amino acid endothelin-1 (ET-1) , but not big ET-1, induced eosinophil migration into the injected loci with a peak after administration for 12 h, and increased the levels of eotaxin and interleukin-5 with peaks at 6 and 24 h, respectively
Shiu et al., Eur J Haematol 2002 (Anemia, Sickle Cell...) : The presence of interleukin-1 in the perfusion system, as a model for inflammatory cytokine effects, enhanced the overall amounts of released prostacyclin but did not affect the production of endothelin-1
Ohshima et al., Int Arch Allergy Immunol 2002 : LTE ( 4 ) also induced significant eosinophil migration at 10 ( -6 ) M. LTD ( 4 ) enhanced EDN release induced by IL-5 via CysLT ( 1 )
Stankevicius et al., Medicina (Kaunas) 2003 (Arteriosclerosis...) : The synthesis of endothelin-1 is induced by hypoxia, thrombin, interleukin-1 , transforming growth factor-beta1, vasopressin, and catecholamines
Matsuwaki et al., Pharmacology 2005 : We investigated the effect of a PPARgamma agonist on human eosinophil functions such as IL-5 induced CD69 surface expression and EDN release ... IL-5 induced eosinophil CD69 surface expression and EDN release were significantly inhibited by the synthetic PPARgamma agonist troglitazone, and these effects were reversed by a PPARgamma antagonist
Kolb et al., Z Gesamte Inn Med 1991 (Anoxia...) : The synthesis of endothelin 1 in the endothelial cells is stimulated by adrenaline, noradrenaline, angiotensin II, arginine-vasopressin, thrombine, interleukin 1 and hypoxia
Ito et al., Int Arch Allergy Immunol 2008 : Treatment with HGF suppressed interleukin-5 induced upregulation of CD69 expression, ROS production and EDN release from human eosinophils