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CHUK — CXCL1

Text-mined interactions from Literome

Devalaraja et al., Cancer Res 1999 (Melanoma) : Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription
Yang et al., Cancer Res 2001 (Melanoma) : Moreover, recombinant CXCL1 can directly induce IKK activity in normal human epidermal melanocytes in a concentration dependent manner after up-modulation of CXCL1 protein expression, whereas inhibition of IKKbeta activity results in down-modulation of CXCL1 protein expression
Yang et al., Clin Cancer Res 2006 (Melanoma) : Inhibition of constitutive IKK activity by BMS-345541 resulted in the reduction of NF-kappaB activity, CXCL1 chemokine secretion by cultured melanoma cells and melanoma cell survival in vitro and in vivo
Edwards et al., Mol Immunol 2007 : Focusing on CXCL8, both rhinovirus infection and dsRNA treatment required IkappaB kinase-beta for induction of CXCL8