Gene interactions and pathways from curated databases and text-mining

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CUL1 — TPO

Text-mined interactions from Literome

Ema et al., J Exp Med 2000 : In the presence of stem cell factor (SCF) , thrombopoietin (TPO) induced a first cell division of CD34 ( - ) KSL cells more efficiently than did interleukin (IL)-3 or IL-6
Fujiki et al., Exp Hematol 2002 : Moreover, the endogenous production of TPO by cultured CD34 ( + ) IL-6R ( - ) cells in the presence of Epo+SCF+IL-9 was ruled out by reverse transcriptase polymerase chain reaction for TPO mRNA
Yoshikubo et al., Exp Hematol 2006 : Human UCB CD34 ( + ) cells were stably expanded on MS-5 stroma cells in the presence of SCF , FL, and TPO
Dolzhanskiy et al., Blood 1997 : SCF alone had no effect on MK proliferation in the absence of TPO, but increased both MK number and CFU-MK by 1.5- to 2.0-fold in the presence of TPO