Gene interactions and pathways from curated databases and text-mining

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AKT1 — CSK

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dey et al., Exp Cell Res 2005 : CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity ... These data suggest a distinct requirement for CSK in the regulation of NGF/TrkA activation of RAS, RAC, ERK, and AKT via the differential control of SFKs in the orchestration of neuronal differentiation
Chaurasia et al., Mol Cell Biol 2010 (Sepsis) : Furthermore, primary macrophages derived from PDK-1 ( Deltamyel ) mice lack LPS- and Pam3CSK4 stimulated AKT activity but exhibit increased mRNA expression and release of tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6)