Anand-Srivastava et al., Peptides 2005
:
Furthermore, the activation of NPR-C receptor by C-ANP ( 4-23 ) and CNP inhibits the mitogen activated protein kinase activity stimulated by endothelin-3, platelet derived growth factor, phorbol-12 myristate 13-acetate, suggesting that NPR-C receptor might also be coupled to other signal transduction system or that there may be an interaction of the NPR-C receptor and some other signaling pathways
Khambata et al., Br J Pharmacol 2011
:
Activation of ERK 1/2 by CNP was inhibited by Pertussis toxin ( 100 ng·mL?1 ) and M372049 ( 10 µM )