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CEBPB — IGF1
Text-mined interactions from Literome
McCarthy et al., Endocrinology 2000
:
These events appear to converge on the important
role of C/EBPdelta and
C/EBPbeta on
IGF-I expression by osteoblasts
LaVoie et al., Endocrinology 2004
:
These data indicate that GATA-4 and
C/EBPbeta are both
required for FSH +/-
IGF-I stimulation of the porcine steroidogenic acute regulatory protein gene promoter in homologous granulosa cell cultures
Chang et al., J Biol Chem 2004
:
In osteoblasts
C/EBPbeta can
increase insulin-like growth factor I (IGF-I) transcription following treatment with hormones that activate protein kinase A, but little is known as yet about the expression of C/EBPbeta itself in these cells
Lee et al., Mol Pharmacol 2007
(Carcinoma, Hepatocellular...) :
IGF-1 caused the nuclear translocation of
CCAAT/enhancer binding protein beta ( C/EBPbeta ), which might be responsible for XRE activation
Staiger et al., Carcinogenesis 2009
(Adenocarcinoma...) :
Thus,
C/EBPbeta contributes to endocrine expression of
IGF-1 , leptin and insulin, which modulate energy balance and can contribute to cancer progression by creating a favorable environment for tumor cell proliferation and survival