Gene interactions and pathways from curated databases and text-mining

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CDH5 — PRKAR2A

Text-mined interactions from Literome

Jin et al., Blood 2010 : Activated PKA blocks pp60Src dependent vascular endot helial-cadherin phosphorylation, thereby stimulating cell-cell adhesion while suppressing endothelial cell polarization, motility, angiogenesis, and vascular permeability
Ishiguro et al., Curr Neurovasc Res 2011 (Hypoxia-Ischemia, Brain) : P13-K inhibition by LY294002 had no influence on the effects of cilostazol, but inhibition of cAMP/PKA with PKA inhibitor and Rp-cAMPS suppressed cilostazol induced inhibition of cell damage and promotion of VE-cadherin expression