◀ Back to PLD3

CDC42 — PLD3

Text-mined interactions from Literome

Walker et al., J Biol Chem 2000 : Activation of phospholipase D1 by Cdc42 requires the Rho insert region
Yoon et al., Biochem Biophys Res Commun 2006 : To examine the effect of Cdc42 on PLD activation and neurite outgrowth, we transfected dominant negative Cdc42 ( Cdc42N17 ) and constitutively active Cdc42 ( Cdc42V12 ) into neural stem cells, respectively ... On the other hand, Cdc42V12 increased both PLD activity and neurite outgrowth, suggesting that active state of Cdc42 is important in upregulation of PLD activity which is responsible for the increase of neurite outgrowth
Bae et al., J Biol Chem 1998 : In conclusion, the present study shows that conserved amino acids in the switch I region of RhoA are major PLD interaction sites and that residues in the switch II and internal regions are responsible for the differential activation of PLD by RhoA and Cdc42Hs