Gene interactions and pathways from curated databases and text-mining

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BAD — IGF1

Text-mined interactions from Literome

Ahmad et al., J Immunol 2000 : In F/B cells, IGF-1 induced phosphorylation of the apoptotic protein BAD was inhibited by the PDE3 inhibitor cilostamide
Mehrhof et al., Circulation 2001 : IGF-I-stimulation was followed by a PI3K dependent phosphorylation of AKT and BAD and an MEK1 dependent phosphorylation of extracellular signal regulated kinase ( ERK ) 1 and ERK2
Gilmore et al., J Biol Chem 2002 (MAP Kinase Signaling System) : Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor ... Moreover, we demonstrate that IGF transactivates the EGF receptor and that ZD1839 blocks IGF mediated phosphorylation of MAPK and BAD
Liu et al., Endocrinology 2002 : IGF-I increased the phosphorylation of glycogen synthase kinase 3beta, BAD , FKHR, and p70 ( S6 ) kinase
Freilinger et al., Oncogene 2006 (Tuberous Sclerosis) : Tuberin interferes with insulin-like growth factor-1 induced BAD Ser136 phosphorylation and cell survival