Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ATP1A2
→
MAPK3
(increases, MAPK3 Activity, ATP1A2 Activity)
Al-Khalili et al., J Biol Chem 2004* Evidence: Insulin-stimulated Na(+),K(+)-ATPase activation, phosphorylation, and translocation of alpha-subunits to the plasma membrane were abolished by 20 microm PD98059, which is an inhibitor of MEK1/2, an upstream kinase of ERK1/2. Furthermore, inhibitors of phosphatidylinositol 3-kinase (100 nm wortmannin) and protein kinase C (10 microm GF109203X) had similar effects.