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ANXA6 — HIF1A

Text-mined interactions from Literome

Skinner et al., J Biol Chem 2004 (Ovarian Neoplasms) : HDM2 and p70S6K1 are two downstream targets of AKT that mediate growth factor induced VEGF transcriptional activation and HIF-1alpha expression
Zhou et al., Carcinogenesis 2007 (Neovascularization, Pathologic...) : These results suggest that insulin induced HIF-1alpha and VEGF expression through H2O2 production and p70S6K1 activation in prostate cancer cells
Lee et al., Clin Cancer Res 2006 (Neoplasm Invasiveness...) : In OVCAR-3 and PC-3 cells, the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin/p70S6K and p42/p44 mitogen activated protein kinase pathways were required for LPA induced HIF-1alpha and VEGF expressions, whereas only the phosphoinositide 3-kinase/mammalian target of rapamycin/p70S6K pathway was important in SK-Hep1 cells