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ALK — IL22
Text-mined interactions from Literome
Bard et al., Leukemia 2008
(Lymphoma, Large-Cell, Anaplastic...) :
Nucleophosmin
(NPM)-ALK , the characteristic fusion gene oncoprotein expressed in ALK ( + ) ALCL, directly
contributes to the aberrant expression of
IL-22R1 , as transfection of NPM-ALK in Jurkat cells induced IL-22R1 expression and IL-22 mediated STAT3 activation
Savan et al., Blood 2011
(Inflammation...) :
This study documents a previously unknown role of IL-22R1 in inflammation and identifies the
involvement of
IL-22R1/IL-22 in
ALK ( + ) ALCL