Gene interactions and pathways from curated databases and text-mining

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ALK — IL22

Text-mined interactions from Literome

Bard et al., Leukemia 2008 (Lymphoma, Large-Cell, Anaplastic...) : Nucleophosmin (NPM)-ALK , the characteristic fusion gene oncoprotein expressed in ALK ( + ) ALCL, directly contributes to the aberrant expression of IL-22R1 , as transfection of NPM-ALK in Jurkat cells induced IL-22R1 expression and IL-22 mediated STAT3 activation
Savan et al., Blood 2011 (Inflammation...) : This study documents a previously unknown role of IL-22R1 in inflammation and identifies the involvement of IL-22R1/IL-22 in ALK ( + ) ALCL