Gene interactions and pathways from curated databases and text-mining

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AGTR1 — AKT1

Text-mined interactions from Literome

Janelidze et al., Neurobiol Dis 2001 (Ischemic Attack, Transient) : Phosphorylation of Akt1 on Ser473 transiently increased at 1 and 4 h of reperfusion, whereas phosphorylation of Akt1 on Thr308 was reduced during reperfusion
Kawahara et al., J Cardiovasc Pharmacol 2005 (Hypertension) : Recent studies have shown that angiotensin II type 1 (AT1) receptor mediated Akt activation induces vascular smooth muscle cell ( VSMC ) dedifferentiation in vitro
Olivares-Reyes et al., Mol Pharmacol 2005 : The dependence of these responses on caveolin was indicated by the finding that cholesterol depletion of C9 cells abolished Ang II-induced inositol phosphate production, activation of Akt/PKB and ERK1/2, and AT(1)-R internalization ... The dependence of these responses on caveolin was indicated by the finding that cholesterol depletion of C9 cells abolished Ang II-induced inositol phosphate production, activation of Akt/PKB and ERK1/2, and AT(1)-R internalization
Yu et al., J Cell Biochem 2007 : Activation of ERK, JNK, Akt , and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells
Wang et al., Biochem Pharmacol 2013 : It was found that mRNA, protein, and current density of K ( Ca ) 3.1 channels were greatly enhanced in cultured cardiac fibroblasts treated with 1 µM Ang II, and the effects were countered by the angiotensin type 1 receptor ( AT1R ) blocker losartan, the p38-MAPK inhibitor SB203580, the ERK1/2 inhibitor PD98059, and the PI3K/Akt inhibitor LY294002