Choi et al., Mol Cell Neurosci 2001
:
Overexpression of cAMP-responsive element binding protein ( CREB ) in Hp-Luc transfected myotubes markedly enhanced the cAMP mediated AChE expression in up- and downregulated chick and human enzymes, respectively
Jung et al., Phytomedicine 2012
(Learning Disorders...) :
Based on these findings, orally administered lancemaside A may be metabolized to echinocystic acid, which may be absorbed into the blood and ameliorate memory and learning deficits by inhibiting AChE activity and inducing BDNF and p-CREB expressions